李钰皓

发布者：周春宇发布时间：2018-03-12浏览次数：4655




李钰皓，上海理工大学，理学院，化学系，副教授，博导。


教育、科研与学术工作经历

2006/09-2011/06南京工业大学，理学院，应用化学，工学博士

2010/12-2012/08美国North Dakota State University，化学系，访问学者、博士后

2012/09-2015/03复旦大学，化学系，博士后

2015/04-2017/05上海理工大学，理学院，师资博士后

2017/06-2018/06上海理工大学，理学院，化学系，讲师

2018/07-至今上海理工大学，理学院，化学系，副教授


教学工作：

主讲本科生课程《有机化学》、《有机合成》、《分析化学》、《普通化学实验》、《有机化学实验》、《分析化学实验》等；研究生课程《绿色能源化学》、《光学成像与分析》，曾荣获上海市高校青年教师教学竞赛三等奖（2020），上海理工大学教学技能竞赛二等奖（2020）。指导大学生创新创业训练计划项目4项（国家级1项）。


科研工作：

主要研究方向为有机无机纳米复合材料的生物传感与智能诊疗应用；有机光功能材料包括非线性光学材料、光致发光材料、化学传感材料等。现任上海市药学会生化与生物技术药物专业委员会委员、上海市生物医学工程学会智慧医学诊断专业委员会委员。迄今发表科研论文50余篇，申请国家发明专利5项，授权2项。

主持科研项目如下：

（1）上海市自然科学基金面上项目（19ZR1434700）

（2）国家自然科学基金青年项目（21501121）

（2）中国博士后科学基金特别项目（2016T90376）

（3）中国博士后科学基金面上项目（2015M581635）

（4）中国博士后科学基金面上项目（2013M541457）

代表性论文：

2021年

  1. Fei Huang, Yuhao Li*, Yuqing Miao, Yun Sun*, et al. Intraperitoneal Injection of Cyanine-Based Nanomicelles for Enhanced Near-Infrared Fluorescence Imaging and Surgical Navigation in Abdominal Tumors, ACS Appl. Bio Mater., 2021, DOI: 10.1021/acsabm.1c00444.

  2. Jie Liu, Jing Zhang, Yuqing Miao, Yun Sun,* Yuhao Li*, et al. Tumor Microenvironment Modulation Platform Based on Composite Biodegradable Bismuth–Manganese Radiosensitizer for Inhibiting Radioresistant Hypoxic Tumors, Small, 2021, DOI: 10.1002/smll.202101015.

  3. Yongtian Liu, Jing Zhang, Yuqing Miao, Yun Sun*, Yuhao Li*, et al. Biodegradable BiOCl Platform for Oxidative Stress Injury–Enhanced Chemodynamic/Radiation Therapy of Hypoxic Tumors, Acta Biomater., 2021, 129, 280-292.

  4. Yao Xu, Yuqing Miao, Yuhao Li*, et al. BSA-encapsulated cyclometalated iridium complexes as nano-photosensitizers for photodynamic therapy of tumor cells, RSC Advances, 2021, 11, 15323-15331.

  5. Yong Deng, Yun Sun*, Yuhao Li*, et al. Dual-light triggered metabolizable nano-micelles for selective tumor-targeted photodynamic/hyperthermia therapy, Acta Biomater., 2021, 119, 323-336.

2020年

  1. Jing Zhang, Yun Sun*, Yuhao Li*, et al. Nanozyme-incorporated biodegradable bismuth mesoporous radiosensitizer for tumor microenvironment-modulated hypoxic tumor thermoradiotherapy, ACS Appl. Mater. Interfaces, 2020, 12, 57768-57781.

  2. Jie Liu, Yun Sun*, Yuhao Li*, et al. X-ray and NIR light dual-triggered mesoporous upconversion nanophosphor/Bi heterojunction radiosensitizer for highly efficient tumor ablation, Acta Biomater., 2020, 113, 570-583.

  3. Guangcong Zhang, Jie Liu, Jimin Zhu*, Shuqiang Wen*, Yuhao Li*, et al. Bismuth-based mesoporous nanoball carrying sorafenib for computed tomography imaging and synergetic chemoradiotherapy of hepatocellular carcinoma, Adv. Healthc. Mater., 2020, 2000650.

  4. Xiaojia Qin, Jie Liu, Yuhao Li*, Yingjian Zhang, Yun Sun*, et al. Mesoporous Bi-containing radiosensitizer loading with DOX to repolarize tumor-associated macrophages and elicit immunogenic tumor cell death to inhibit tumor progression, ACS Appl. Mater. Interfaces, 2020, 12, 31225-31234.

  5. Yong Deng, Yun Sun*, Yuhao Li*, et al. PEGylated iridium-based nano-micelle: Self-assembly, selective tumor fluorescence imaging and photodynamic therapy, Dyes Pigments, 2020, 182, 108651.

  6. Xiangnan Yu,‡ Yong Deng,‡Yuhao Li*, Jimin Zhu*, et al. Sorafenib-conjugated zinc phthalocyanine-based nanocapsule for trimodal therapy in an orthotopic hepatocellular carcinoma xenograft mouse model, ACS Appl. Mater. Interfaces, 2020, 12, 17193-17206.

  7. Yong Deng, Yun Sun*, Yuhao Li*, et al. Electrostatic self-assembled iridium(III) nano-photosensitizer for selectively disintegrated and mitochondria targeted photodynamic therapy, Dyes Pigments, 2020, 175, 108105.

2019年

  1. Jie Liu, Yuhao Li*, Yuqing Miao* and Yun Sun*, et al. Ultrafast synthesizing bismuth mesoporous nanolitchi radiosensitizer loading high dose DOX for CT-guided enhanced chemoradiotherapy, ACS Appl. Mater. Interfaces, 2019, 11, 42932-42942. (Cover paper)

  2. Yuhao Li, Jie Liu, Yun Sun*, et al. Ultrafast synthesis of fluorine-18 doped bismuth based upconversion nanophosphors for tri-modal CT/PET/UCL imaging in vivo, Chem. Commun., 2019, 55, 7259-7262.

  3. Yuhao Li*, Yuqing Miao, et al. A near-infrared frequency upconversion probe for nitroreductase detection and hypoxia tumor in vivo imaging, Sensor. Actuat. B Chem., 2019, 286, 337-345.

  4. Yuhao Li*, Yuqing Miao, et al. An AEE-active probe combined with cyanoacrylate fuming for a high resolution fingermark optical detection, Sensor. Actuat. B Chem., 2019, 283, 99-106.

2017年

  1. Yuhao Li*, Yun Sun*, Yuqing Miao, et al. A cation-exchange controlled core-shell MnS@Bi2S3 theranostic platform for multimodal imaging guided radiation therapy with hyperthermia boost, Nanoscale, 2017, 9, 14364-14375. (Back cover paper)

  2. Yuhao Li*, Rui Liu*, Yuqing Miao*, et al. SiO2 encapsulated nanofluorophor: photophysical properties, aggregation induced emission and its application for cell mitochondria imaging, Dyes Pigments, 2017, 139, 110-117.

Before 2017年

  1. Yuhao Li*, Yuqing Miao*, et al. NiCoP Nanoparticles as efficient electrocatalyst for oxygen evolution reaction in an alkaline solution, Int. J. Electrochem. Sci., 2016, 11, 9917-9927.

  2. Yuhao Li, Wei Feng*, Fuyou Li*, et al. Ultrasensitive near-infrared fluorescence-enhanced probe for in vivo nitroreductase imaging, J. Am. Chem. Soc., 2015, 137 (19), 6407-6416. (ESI高被引论文)

  3. Yuhao Li, Wenfang Sun*, et al. Effects of extended π-conjugation in phenanthroline (N^N) and phenylpyridine (C^N) ligands on the photophysics and reverse saturable absorption of cationic heteroleptic iridium(III) complexes, J. Phys. Chem. C, 2014, 118, 6372-6384.

  4. Yuhao Li, Wenfang Sun*, et al. Synthesis and photophysics of reverse saturable absorbing heteroleptic iridium(III) complexes bearing 2-(7-r-fluoren-2'-yl)pyridine ligands, Dalton Trans., 2014, 43, 1724-1735.

  5. Yuhao Li, Rui Liu*, Fuyou Li*, et al. A bioprobe based on aggregation induced emission (AIE) for cell membrane tracking, Chem. Commun., 2013, 49, 11335-11337.

  6. Yuhao Li, Wenfang Sun*, et al. Nonlinear absorbing cationic iridium(III) complexes bearing benzothiazolylfluorene motif on the bipyridine (N^N) ligand: synthesis, photophysics and reverse saturable absorption, ACS Appl. Mater. Interfaces, 2013, 5, 6556-6570.

  7. Yuhao Li, Wenfang Sun*, et al. Long-lived π-shape platinum(II) diimine complexes bearing 7-benzothiazolylfluoren-2-yl motif on the bipyridine and acetylide ligands: admixing π,π* and charge transfer configurations, J. Phys. Chem. C, 2013, 117, 5908-5918.

  8. Yuhao Li, Hongjun Zhu*, et al. Synthesis, Insecticidal activity, and structure-activity relationship (SAR) of anthranilic diamides analogous containing oxadiazole ring, Org. Biomol. Chem., 2013, 11, 3979-3988.

（截止2021/07）


联系方式：

E-mail：yhli@usst.edu.cn



 


 

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